MINNEAPOLIS (AP) -- Tarvaris Jackson came off the bench for the injured Brett Favre and threw for 187 yards and two touchdowns, and the Minnesota Vikings defense dominated Buffalo in a 38-14 victory on Sunday.
Adrian Peterson rushed for 107 yards and three touchdowns on a gimpy right ankle for the Vikings (5-7), who are 2-0 under interim head coach Leslie Frazier.
Favre injured his throwing shoulder on the first series of the game after a big hit by Bills linebacker Arthur Moats. Jackson came in and led the Vikings to 31 first-half points. But he also threw three interceptions, including one that Drayton Florence returned 40 yards for a touchdown.
Florence had two interceptions for the Bills (2-10). Buffalo committed five turnovers and had just 9 yards passing in the first half to lose its second in a row following two straight wins.
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